Fig. 4

Induction of histological improvement by add-on GUT-1. A Rates of histological improvement at baseline (BL) and week 6. B Individual Nancy histological index at baseline (BL, dotted blue) and the end of induction study (week 6; W6, dotted pink). Lines indicate mean values. C Typical histological findings from baseline (BL, left panels) to week 6 (right panels) in 3 corticosteroid-dependent UC patients (case 1, 4 and 5) are shown. HE findings of the heaviest inflammation at week 0 and 6. Original magnification, × 200