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Table 1 Demographic and baseline characteristics

From: Add-on multiple submucosal injections of the RNA oligonucleotide GUT-1 to anti-TNF antibody treatment in patients with moderate-to-severe ulcerative colitis: an open-label, proof-of concept study

 

GUT-1

(n = 5)

Male (n)

4

Female (n)

1

Mean age (years)

38.2

Mean duration of disease (years)

5.8

Mean Endoscopy Subscore

2.4

UC location: n (%)

 Left-sided colitis

5 (100)

Mean modified Mayo Score (mMS)

7.8

Anti-TNF antibodies: n (%)

 Infliximab (IFX)

3 (60)

 Adalimumab (ADA)

2 (40)

Refractory to prior anti-TNF antibody: n (%)

5 (100)

Concomitant anti-TNF antibody: n (%)

5 (100)

Concomitant corticosteroid: n (%)

3 (60.0)

Concomitant thiopurine: n (%)

3 (60.0)

Concomitant tacrolimus: n (%)

2 (40.0)

Concomitant 5-ASA: n (%)

5 (100)